Anti- Metapneumovirus Phosphoprotein antibody [hMPV 123],Abcam,AB94803

Fusion partner: PS-NS/1-Ag4

Host

Mouse

Reactivity

Metapneumovirus

Application

ICC/IF, ELISA, WB, IHC-Fr

Platform ID

BAB821328775

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti- Metapneumovirus Phosphoprotein antibody [hMPV 123]
Cat. No.AB94803
HostMouse
IsotypeIgG2a
ReactivityMetapneumovirus
ApplicationICC/IF, ELISA, WB, IHC-Fr
ClonalityMonoclonal
Clone NumberhMPV 123
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays critical roles in regulating RNA replication and transcription through its interactions with multiple proteins (By similarity). Tethers the RNA-directed RNA polymerase L to the nucleoprotein-RNA complex (PubMed : 31698413). Recruits the M2-1 protein, a processivity factor that is required for efficient transcription of viral RNA (By similarity). Acts as a chaperone for neo-synthesized nucleoprotein by forming an N-P complex that preserves N in a monomeric and RNA-free state and prevents the association of nascent N with host cell RNAs (By similarity). Recruits the host phosphatase PP1 to inclusion bodies to regulate viral transcription (By similarity). See full target information P

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