Anti-Mineralocorticoid Receptor antibody [H10E4C9F],Abcam,AB2774

Host

Mouse

Reactivity

Human

Application

Flow Cyt, ICC/IF, IHC-P

Platform ID

BAB135534206

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Mineralocorticoid Receptor antibody [H10E4C9F]
Cat. No.AB2774
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt, ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberH10E4C9F
Concentration1.4 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels. See full target information NR3C2

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