Anti-Mitofusin 1 antibody [11E91H12],Abcam,AB126575

What is this antibody validated in? Anti-Mitofusin 1 antibody [11E91H12] (ab126575) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF) in Mouse, Rat samples. What is the molecular weight of Mitofusin 1? Anti-Mitofusin 1 [11E91H12] (ab126575) specifically detects a band for Mitofusin 1 (UniProt: Q811U4) at a molecular weight of 84kDa. Trusted by the scientific community Anti-Mitofusin 1 [11E91H12] (ab126575) was first used in a scientific publication in 2012 and has been cited over 20 times in peer-reviewed journals. Other related products We have a range of other formats of antibody clone [11E91H12] also available for your convenience: ab126575, HRP - ab198410 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Rat

Application

ICC/IF, WB

Platform ID

BAB448540213

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Mitofusin 1 antibody [11E91H12]
Cat. No.AB126575
HostMouse
IsotypeIgG2b
ReactivityMouse, Rat
ApplicationICC/IF, WB
ClonalityMonoclonal
Clone Number11E91H12
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityPrecipitation Ammonium Sulphate
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.02% Sodium azide Constituents: 99% HEPES buffered saline
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed : 12527753, PubMed : 15297672, PubMed : 23921378, PubMed : 24513856). Membrane clustering requires GTPase activity (By similarity). It may involve a major rearrangement of the coiled coil domains (PubMed : 15297672). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed : 12527753). Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity (By similarity). See full target information Mfn1

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