Anti-Mitofusin 1 antibody [EPR21953-74],Abcam,AB221661

What is this antibody validated in? Anti-Mitofusin 1 antibody [EPR21953-74] (ab221661) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP) in Mouse, Rat samples. What is the molecular weight of Mitofusin 1? Anti-Mitofusin 1 [EPR21953-74] (ab221661) specifically detects a band for Mitofusin 1 (UniProt: Q811U4) at a molecular weight of 84kDa. Trusted by the scientific community Anti-Mitofusin 1 [EPR21953-74] (ab221661) was first used in a scientific publication in 2019 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR21953-74] also available for your convenience: ab221661, Carrier free - ab254198 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB, IP

Platform ID

BAB761046460

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Mitofusin 1 antibody [EPR21953-74]
Cat. No.AB221661
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationWB, IP
ClonalityMonoclonal
Clone NumberEPR21953-74
Concentration0.579 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed : 12527753, PubMed : 15297672, PubMed : 23921378, PubMed : 24513856). Membrane clustering requires GTPase activity (By similarity). It may involve a major rearrangement of the coiled coil domains (PubMed : 15297672). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed : 12527753). Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity (By similarity). See full target information Mfn1

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