Anti-Mitofusin 1 antibody - N-terminal,Abcam,AB191853

Target data Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed : 12475957, PubMed : 12759376, PubMed : 27920125, PubMed : 28114303). Membrane clustering requires GTPase activity (PubMed : 27920125). It may involve a major rearrangement of the coiled coil domains (PubMed : 27920125, PubMed : 28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed : 12475957, PubMed : 12759376). Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed : 12759376). Has low GTPase activity (PubMed : 27920125, PubMed : 28114303). See full target information MFN1