Anti-Mitofusin 2 + Mitofusin 1 antibody [3C9],Abcam,AB57602

What is this antibody validated in? Anti-Mitofusin 2 + Mitofusin 1 antibody [3C9] (ab57602) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Cynomolgus monkey, Human, Mouse, Rat samples. What is the molecular weight of Mitofusin 1? Anti-Mitofusin 2 + Mitofusin 1 [3C9] (ab57602) specifically detects a band for Mitofusin 1 (UniProt: Q8IWA4) at a molecular weight of 84kDa. Trusted by the scientific community Anti-Mitofusin 2 + Mitofusin 1 [3C9] (ab57602) was first used in a scientific publication in 2007 and has been cited over 200 times in peer-reviewed journals. Reviewed by scientists Anti-Mitofusin 2 + Mitofusin 1 [3C9] (ab57602) has over 10 independent reviews from customers.

Host

Mouse

Reactivity

Human, Rat, Cynomolgus monkey, Mouse

Application

IP, Flow Cyt, ICC/IF, IHC-P, WB

Platform ID

BAB198615177

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Mitofusin 2 + Mitofusin 1 antibody [3C9]
Cat. No.AB57602
HostMouse
IsotypeIgG2a
ReactivityHuman, Rat, Cynomolgus monkey, Mouse
ApplicationIP, Flow Cyt, ICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone Number3C9
ImmunogenRecombinant Full Length Protein corresponding to Human MFN1.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: 91% Water, 8% Sodium chloride, 0.6% Disodium hydrogenorthophosphate, 0.2% Potassium chloride, 0.2% Potassium phosphate monobasic
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed : 12475957, PubMed : 12759376, PubMed : 27920125, PubMed : 28114303). Membrane clustering requires GTPase activity (PubMed : 27920125). It may involve a major rearrangement of the coiled coil domains (PubMed : 27920125, PubMed : 28114303). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed : 12475957, PubMed : 12759376). Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed : 12759376). Has low GTPase activity (PubMed : 27920125, PubMed : 28114303). See full target information MFN1 Additional targets MFN2

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