Anti-Mouse ADAM-19 monoclonal antibody Anti-Mouse 100 µg,Reliatech,103-M302

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of A Disintegrin and Metalloprotease-like Domain 19 ectodomain (ADAM19).

Host

Rat

Reactivity

Mouse

Application

WB

Platform ID

BAB245472905

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Reliatech

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAnti-Mouse ADAM-19 monoclonal antibody Anti-Mouse 100 µg
Cat. No.103-M302
Accession NumberO35674
HostRat
IsotypeIgG2
ReactivityMouse
ApplicationWB
Working DilutionsWB: 1:500-1000.
Clone Number(#11J23)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

ADAM-19 (a disintegrin and metalloprotease 19; also MADDAM and Meltrinβ) is a 95-100 kDa member of the M12B peptidase family of enzymes. It is expressed on multiple cell types including monocytes, fibroblasts, osteoblasts and dendritic cells. After cleavage of a signal sequence and prodomain, the ectodomain circulates in plasma bound to α2 Macroglobulin. ADAM19 cleaves at sequences present in myelin basic protein, insulin β chain, TNFα, TRANCE and SCF. Over amino acids (aa) 205-705, mouse ADAM19 shares 87% aa sequence identity with human ADAM19.

Synonyms

Adam19; M[b]; Mltnb; AL024287

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.