Anti-Mucin 5AC antibody [2-11M1],Abcam,AB24071
This antibody reacts with peptide core of gastric mucin restricted to the surface gastric epithelium. It characterised the M1-b epitope, completely destroyed by b-mercapto-ethano. The M1-b epitope is found located on a 58 kD and 40 kD peptide after trypsin treatment of native M1 mucin. This M1-b epitope coprecipites with the M1-f epitope encoded by Mucin 5AC gene. It is probably associated with the gastric mucin encoded by Mucin 5AC gene or with a gastric mucin encoded by another gastric MUC gene which polymerized with the M1/Mucin 5AC gastric mucin.
Host
Mouse
Reactivity
Human
Application
Flow Cyt
Platform ID
BAB892006098
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-Mucin 5AC antibody [2-11M1]
Cat. No.AB24071
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt
ClonalityMonoclonal
Clone Number2-11M1
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human MUC5AC.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system (PubMed : 14535999, PubMed : 14718370). Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD) (PubMed : 14535999). See full target information MUC5AC
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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