Anti-Mucin 5AC antibody [45M1],Abcam,AB3649

This product has switched from a hybridoma to recombinant production method on 8 th March 2021. Product Specifications Anti-Mucin 5AC antibody [45M1] (ab3649) is a mouse recombinant monoclonal antibody and is validated for use in ICC/IF, IHC-Fr, IHC-P, mIHC in human, mouse, rat samples. Anti-Mucin 5AC antibody [45M1] (ab3649) specifically detects Mucin 5AC (UniProt ID: P98088; Molecular weight: 583kDa) and is sold in a convenient trial size to enable initial testing (20 µg) and larger sizes for subsequent scaling up experiments (100 µg and 1 mg). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Mucin 5AC antibody [45M1] (ab3649) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Mucin 5AC antibody [45M1] (ab3649) has been cited over 146 times in peer reviewed journals and is trusted by the scientific community. Anti-Mucin 5AC antibody [45M1] (ab3649) has 6 independent reviews from customers. Related Products Conjugation-ready, carrier free format available for antibody clone 45M1 - ab264494 . Antibody clone 45M1 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647 ( ab309610 , ab309611 ). What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Mouse

Reactivity

Mouse, Rat, Human

Application

ICC/IF, IHC-P, IHC-Fr, mIHC

Platform ID

BAB204512345

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Mucin 5AC antibody [45M1]
Cat. No.AB3649
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Human
ApplicationICC/IF, IHC-P, IHC-Fr, mIHC
ClonalityMonoclonal
Clone Number45M1
Concentration0.938 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system (PubMed : 14535999, PubMed : 14718370). Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD) (PubMed : 14535999). See full target information MUC5AC

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