Anti-Myelin Basic Protein antibody [EPR21188] - Oligodendrocyte Marker,Abcam,AB218011
Anti-Myelin Basic Protein antibody [EPR21188] (ab218011) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-Fr, IHC-P, WB in human, mouse, rat samples. Anti-Myelin Basic Protein antibody [EPR21188] (ab218011) has been cited over 28 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-Myelin Basic Protein antibody [EPR21188] (ab218011) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Myelin Basic Protein antibody [EPR21188] (ab218011) has 4 independent reviews from customers. Anti-Myelin Basic Protein antibody [EPR21188] (ab218011) specifically detects Myelin Basic Protein (UniProt ID: P04370; Molecular weight: 27kDa) and is sold in 100 uL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR21188 - ab23378 . Antibody clone EPR21188 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 594, Alexa Fluor® 568, Alexa Fluor® 488, Alexa Fluor® 555 (ab31179, ab31371 , ab314162 , ab315358 ). Myelin Basic Protein (MBP) is a key component of the myelin sheath and is extensively studied in neuroscience. It is crucial for maintaining myelin integrity and ensuring effective nerve signal transmission. Changes in MBP expression can signal myelin damage, which is significant in various neurodegenerative conditions, such as multiple sclerosis (MS) and Alzheimer's disease (AD). Research on MBP helps in understanding myelin-related pathology and neuronal dysfunction, highlighting its importance in the broader study of neurodegenerative diseases. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IHC-Fr, IHC-P, WB
Platform ID
BAB080649299
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined to optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. See full target information Mbp
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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