Anti-Myeloperoxidase antibody [EPR20257],Abcam,AB208670

Anti-Myeloperoxidase antibody [EPR20257] (ab208670) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB. Anti-Myeloperoxidase antibody [EPR20257] (ab208670) was first used in a scientific publication in 2018 and has been cited over 162 times in peer reviewed journals. It's performance in IHC and Western Blot in mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Myeloperoxidase antibody [EPR20257] (ab208670) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Myeloperoxidase antibody [EPR20257] (ab208670) has 5 independent reviews from customers. Anti-Myeloperoxidase antibody [EPR20257] (ab208670) specifically detects Myeloperoxidase (UniProt ID: P05164; Molecular weight: 79kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR20257 - ab221847 . Antibody clone EPR20257 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Biotin ( ab225474 , ab322301 ). - Recombinant format for unrivalled batch-batch consistency: no need for same-lot requests Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, ICC/IF, WB, Flow Cyt (Intra)

Platform ID

BAB893505378

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Myeloperoxidase antibody [EPR20257]
Cat. No.AB208670
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, ICC/IF, WB, Flow Cyt (Intra)
ClonalityMonoclonal
Clone NumberEPR20257
Concentration0.509 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed : 9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed : 25698971). See full target information MPO

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