Anti-Myeloperoxidase antibody [EPR20257] - Rat IgG2a (Chimeric),Abcam,AB300650

What is this antibody validated in? Anti-Myeloperoxidase antibody [EPR20257] - Rat IgG2a (Chimeric) (ab300650) is a rat recombinant monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR20257] also available for your convenience: ab208670 , Carrier free - ab221847 , Alexa Fluor® 488 - ab225474 , ab300650, Carrier free - ab300651 , Biotin - ab322301 , HRP - ab323726 What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rat

Reactivity

Human, Mouse, Rat

Application

Flow Cyt (Intra), ICC/IF, IHC-P

Platform ID

BAB518517872

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Myeloperoxidase antibody [EPR20257] - Rat IgG2a (Chimeric)
Cat. No.AB300650
HostRat
IsotypeIgG2a
ReactivityHuman, Mouse, Rat
ApplicationFlow Cyt (Intra), ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumberEPR20257
Concentration0.978 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityIon exchange chromatography
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed : 9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed : 25698971). See full target information MPO

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