Anti-Myosin VIIa/MYO7A antibody [EPR7497],Abcam,AB150386

What is this antibody validated in? Anti-Myosin VIIa/MYO7A antibody [EPR7497] (ab150386) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Myosin VIIa/MYO7A? Anti-Myosin VIIa/MYO7A [EPR7497] (ab150386) specifically detects a band for Myosin VIIa/MYO7A (UniProt: Q13402) at a molecular weight of 254kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR7497] also available for your convenience: ab150386, Carrier free - ab248957 , APC - ab319262 , PE - ab319410 , Alexa Fluor® 488 - ab319544 , Alexa Fluor® 647 - ab319657 , Alexa Fluor® 594 - ab319761 , Alexa Fluor® 555 - ab319903 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

Flow Cyt (Intra), ICC/IF, WB

Platform ID

BAB832123591

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Myosin VIIa/MYO7A antibody [EPR7497]
Cat. No.AB150386
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationFlow Cyt (Intra), ICC/IF, WB
ClonalityMonoclonal
Clone NumberEPR7497
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. In the retina, plays an important role in the renewal of the outer photoreceptor disks. Plays an important role in the distribution and migration of retinal pigment epithelial (RPE) melanosomes and phagosomes, and in the regulation of opsin transport in retinal photoreceptors. In the inner ear, plays an important role in differentiation, morphogenesis and organization of cochlear hair cell bundles. Involved in hair-cell vesicle trafficking of aminoglycosides, which are known to induce ototoxicity (By similarity). Motor protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing. See full target information MYO7A

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