Anti-NARS antibody,Abcam,AB252995

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, ICC/IF, WB

Platform ID

BAB520816768

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-NARS antibody
Cat. No.AB252995
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, ICC/IF, WB
ClonalityPolyclonal
Concentration0.3 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human NARS1 aa 350-450. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction : asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn) (PubMed : 32738225, PubMed : 32788587, PubMed : 9421509). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells (PubMed : 12235211, PubMed : 30171954). Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells (PubMed : 32788587). See full target information NARS1

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