Anti-NCX1 antibody [C2C12],Abcam,AB2869
Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]
Host
Mouse
Reactivity
Human
Application
IHC-Fr, IHC-P, Flow Cyt (Intra)
Platform ID
BAB584397499
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes (PubMed : 11241183, PubMed : 1374913, PubMed : 1476165). Contributes to Ca(2+) transport during excitation-contraction coupling in muscle (PubMed : 11241183, PubMed : 1374913, PubMed : 1476165). In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum (PubMed : 11241183, PubMed : 1374913, PubMed : 1476165). SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline (PubMed : 11241183, PubMed : 1374913, PubMed : 1476165). Required for normal embryonic heart development and the onset of heart contractions (By similarity). See full target information SLC8A1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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