Anti-NDUFA2 antibody,Abcam,AB198196

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder.

Host

Rabbit

Reactivity

Mouse, Human

Application

IHC-P, WB

Platform ID

BAB959684861

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-NDUFA2 antibody
Cat. No.AB198196
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIHC-P, WB
ClonalityPolyclonal
Concentration0.6 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human NDUFA2.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. See full target information NDUFA2

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