Anti-NDUFS2 antibody [7A12BE5AD5],Abcam,AB110249

Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Rat, Cow, Human

Application

WB, ICC/IF, Flow Cyt

Platform ID

BAB460034693

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-NDUFS2 antibody [7A12BE5AD5]
Cat. No.AB110249
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Cow, Human
ApplicationWB, ICC/IF, Flow Cyt
ClonalityMonoclonal
Clone Number7A12BE5AD5
Concentration1 mg/mL Batch dependent concentration
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.02% Sodium azide Constituents: HEPES buffered saline
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed : 22036843, PubMed : 28031252, PubMed : 30922174). Essential for the catalytic activity of complex I (PubMed : 22036843, PubMed : 30922174). Essential for the assembly of complex I (By similarity). Redox-sensitive, critical component of the oxygen-sensing pathway in the pulmonary vasculature which plays a key role in acute pulmonary oxygen-sensing and hypoxic pulmonary vasoconstriction (PubMed : 30922174). Plays an important role in carotid body sensing of hypoxia (By similarity). Essential for glia-like neural stem and progenitor cell proliferation, differentiation and subsequent oligodendrocyte or neuronal maturation (By similarity). See full target information NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

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