Anti-NEFH antibody [EPR20020] - Neuronal Marker - Chicken IgY (Chimeric),Abcam,AB317042

This Chicken monoclonal chimeric antibody has been engineered from a RabMAb parent antibody ( ab207176 ). By design, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed FC-reactive secondary antibodies are recommended. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Chicken

Reactivity

Human, Mouse, Rat

Application

ICC/IF, IHC-P, WB

Platform ID

BAB398153146

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-NEFH antibody [EPR20020] - Neuronal Marker - Chicken IgY (Chimeric)
Cat. No.AB317042
HostChicken
IsotypeIgY
ReactivityHuman, Mouse, Rat
ApplicationICC/IF, IHC-P, WB
ClonalityMonoclonal
Clone NumberEPR20020
Concentration0.998 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Thiophilic Resin
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Neurofilaments usually contain three intermediate filament proteins : NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). See full target information NEFH

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