Anti-NEK1 antibody,Abcam,AB186519
Host
Rabbit
Reactivity
Human
Application
ICC/IF, IHC-P
Platform ID
BAB523215616
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-NEK1 antibody
Cat. No.AB186519
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, IHC-P
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human NEK1 aa 600-750. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity (PubMed : 20230784). Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed : 20230784). In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed : 20230784). May be implicated in the control of meiosis (By similarity). Involved in cilium assembly (PubMed : 21211617). See full target information NEK1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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