Anti-NFAT5 antibody,Abcam,AB3446
What is this antibody validated in? Anti-NFAT5 antibody (ab3446) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in African green monkey, Human, Mouse samples. What is the molecular weight of NFAT5? Anti-NFAT5 (ab3446) specifically detects a band for NFAT5 (UniProt: O94916) at a molecular weight of 160kDa. Trusted by the scientific community Anti-NFAT5 (ab3446) was first used in a scientific publication in 2003 and has been cited over 30 times in peer-reviewed journals.
Host
Rabbit
Reactivity
Mouse, Human, African green monkey
Application
WB, IHC-P, IP, ICC/IF
Platform ID
BAB900601970
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Transcription factor involved, among others, in the transcriptional regulation of osmoprotective and inflammatory genes. Binds the DNA consensus sequence 5'-[ACT][AG]TGGAAA[CAT]A[TA][ATC][CA][ATG][GT][GAC][CG][CT]-3' (PubMed : 10377394). Mediates the transcriptional response to hypertonicity (PubMed : 10051678). Positively regulates the transcription of LCN2 and S100A4 genes; optimal transactivation of these genes requires the presence of DDX5/DDX17 (PubMed : 22266867). Also involved in the DNA damage response by preventing formation of R-loops; R-loops are composed of a DNA : RNA hybrid and the associated non-template single-stranded DNA (PubMed : 34049076). See full target information NFAT5
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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