Anti-NKAP antibody,Abcam,AB229096

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, WB

Platform ID

BAB276988804

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-NKAP antibody
Cat. No.AB229096
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human NKAP. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a transcriptional repressor (PubMed : 14550261, PubMed : 19409814, PubMed : 31587868). Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development (PubMed : 19409814). Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter. See full target information NKAP

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