Anti-NOTCH3 antibody,Abcam,AB23426
What is this antibody validated in? Anti-NOTCH3 antibody (ab23426) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. What is the molecular weight of NOTCH3? Anti-NOTCH3 (ab23426) specifically detects a band for NOTCH3 (UniProt: Q9UM47) at a molecular weight of 244kDa. Trusted by the scientific community Anti-NOTCH3 (ab23426) was first used in a scientific publication in 2006 and has been cited over 120 times in peer-reviewed journals. Reviewed by scientists Anti-NOTCH3 (ab23426) has over 20 independent reviews from customers.
Host
Rabbit
Reactivity
Human, Mouse
Application
ICC/IF, WB, IHC-P
Platform ID
BAB466731477
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-NOTCH3 antibody
Cat. No.AB23426
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationICC/IF, WB, IHC-P
ClonalityPolyclonal
Concentration0.9 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed : 15350543, PubMed : 14714274). Upon ligand activation through the released notch intracellular domain (NICD), it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). See full target information NOTC3_HUMAN
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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