Anti-NOX2/gp91phox antibody [54.1],Abcam,AB80897

What is this antibody validated in? Anti-NOX2/gp91phox antibody [54.1] (ab80897) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of NOX2/gp91phox? Anti-NOX2/gp91phox [54.1] (ab80897) specifically detects a band for NOX2/gp91phox (UniProt: P04839) at a molecular weight of 65kDa. Trusted by the scientific community Anti-NOX2/gp91phox [54.1] (ab80897) was first used in a scientific publication in 2009 and has been cited over 20 times in peer-reviewed journals.

Host

Mouse

Reactivity

Human

Application

WB, IHC-P, ICC/IF

Platform ID

BAB966881405

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-NOX2/gp91phox antibody [54.1]
Cat. No.AB80897
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB, IHC-P, ICC/IF
ClonalityMonoclonal
Clone Number54.1
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. See full target information CYBB

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