Anti-Nav1.8/SCN10A antibody,Abcam,AB66743

Host

Rabbit

Reactivity

Human

Application

ICC

Platform ID

BAB146129118

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Nav1.8/SCN10A antibody
Cat. No.AB66743
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human SCN10A. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: Whole serum
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms. See full target information SCN10A

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