Anti-Nav1.8/SCN10A antibody [S134],Abcam,AB93616

What is this antibody validated in? Anti-Nav1.8/SCN10A antibody [S134] (ab93616) is a mouse recombinant monoclonal antibody and is validated for use in Immunohistochemistry (IHC-P) in Mouse, Rat samples. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Mouse

Reactivity

Mouse, Rat

Application

IHC-P

Platform ID

BAB083647859

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Nav1.8/SCN10A antibody [S134]
Cat. No.AB93616
HostMouse
IsotypeIgG2a
ReactivityMouse, Rat
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberS134
Concentration0.968 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Rat Scn10a aa 1700 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms. See full target information Scn10a

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