Anti-Necdin antibody,Abcam,AB227908
Host
Rabbit
Reactivity
Mouse
Application
IHC-Fr, WB
Platform ID
BAB772840796
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Necdin antibody
Cat. No.AB227908
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationIHC-Fr, WB
ClonalityPolyclonal
Concentration2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Mouse Ndn aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6.5 - 8.5 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Also functions as a transcription factor and directly binds to specific guanosine-rich DNA sequences. See full target information Ndn
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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