Anti-Nestin antibody [2C1.3A11] - Neural Stem Cell Marker,Abcam,AB18102

What is this antibody validated in? Anti-Nestin antibody [2C1.3A11] (ab18102) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. What is the molecular weight of Nestin? Anti-Nestin [2C1.3A11] (ab18102) specifically detects a band for Nestin (UniProt: P48681) at a molecular weight of 177kDa. Trusted by the scientific community Anti-Nestin [2C1.3A11] (ab18102) was first used in a scientific publication in 2005 and has been cited over 20 times in peer-reviewed journals. Specificity confirmed The specificity of Anti-Nestin antibody [2C1.3A11] (ab18102) has been confirmed by Western blot testing in NES Knockout HAP1 cells.

Host

Mouse

Reactivity

Human

Application

Flow Cyt, IHC-P, ICC/IF, WB

Platform ID

BAB898702882

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Nestin antibody [2C1.3A11] - Neural Stem Cell Marker
Cat. No.AB18102
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt, IHC-P, ICC/IF, WB
ClonalityMonoclonal
Clone Number2C1.3A11
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human NES aa 1450 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.1% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). See full target information NES

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