Anti-Netrin 1 antibody [EPR5428],Abcam,AB126729
What is this antibody validated in? Anti-Netrin 1 antibody [EPR5428] (ab126729) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP) in Human, Mouse, Rat samples. What is the molecular weight of Netrin 1? Anti-Netrin 1 [EPR5428] (ab126729) specifically detects a band for Netrin 1 (UniProt: O95631) at a molecular weight of 67kDa. Trusted by the scientific community Anti-Netrin 1 [EPR5428] (ab126729) was first used in a scientific publication in 2012 and has been cited over 40 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Netrin 1 antibody [EPR5428] (ab126729) has been confirmed by Western blot testing in NTN1 Knockout MCF7 cell line, ab323856 . Other related products We have a range of other formats of antibody clone [EPR5428] also available for your convenience: ab126729, Carrier free - ab201324 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB, IP
Platform ID
BAB961384045

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed : 28483977). Involved in dorsal root ganglion axon projection towards the spinal cord (PubMed : 28483977). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis (PubMed : 15343335). See full target information NTN1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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