Anti-NeuN antibody [EPR12763] - Neuronal Marker,Abcam,AB177487

Anti-NeuN antibody [EPR12763] - Neuronal Marker (ab177487) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC (PFA fixed), IHC-Fr, IHC-P, WB, mIHC in cat, common marmoset, dog, human, mouse, rat, sheep, zebrafish samples. Anti-NeuN antibody (anti-RBFOX3 antibody) [EPR12763] - Neuronal Marker (ab177487) has been cited over 868 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure NeuN antigen antibody (ab177487) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-NeuN antibody [EPR12763] - Neuronal Marker (ab177487) has 72 independent reviews from customers. Anti-NeuN antibody [EPR12763] - Neuronal Marker (ab177487) specifically detects NeuN (UniProt ID: A6NFN3; Molecular weight: 34kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR12763 - ab209898 . Antibody clone EPR12763 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647, Biotin, Alexa Fluor® 594 ( ab190195 , ab190565 , ab204681 , ab207279 ). NeuN (RBFOX3) is a protein extensively used as a neuronal marker due to its expression in the nuclei and cytoplasm of neurons. It is vital for the regulation of alternative splicing of pre-mRNA, which is essential for neural development and function. Mutations or dysregulation of RBFOX3 have been associated with various neurological conditions, including autism spectrum disorder, cognitive deficits, and epilepsy, highlighting its importance in maintaining normal brain function. Browse our curated portfolio of extensively validated antibodies and assays, with antibodies to over 90% of key targets in major glioblastoma pathways– including EGF, VEGF, MAPK, Wnt, NFKB, and PI3K/AkT/MTOR – all in one place. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Shipping conditions update: ambient shipping This product will be delivered at ambient temperature instead of chilled – this is by design. Extensive stability testing confirmed that our products are suitable for shipment under ambient conditions and maintain expected quality. Why the change? It’s part of our commitment to more sustainable packaging solutions, with ambient deliveries using eco-friendly materials such as recyclable cardboard instead of polystyrene. What you need to know Ambient shipments come clearly marked on the delivery note. No ice will be included in ambient shipments, but mixed orders (ambient and cold-chain items) will still arrive with ice packs to protect temperature-sensitive products. Warranty coverage remains fully valid, aligned with our validated shipping method. Please store the product as per the datasheet instructions upon receipt. Find out more - https://www.abcam.com/en-us/support/shipping-storage-support/ambient-shipping

Host

Rabbit

Reactivity

Mouse, Rat, Sheep, Goat, Cat, Dog, Human, Zebrafish, Common marmoset

Application

Flow Cyt (Intra), mIHC, IHC-Fr, ICC/IF, WB, IHC-P, IHC (PFA fixed)

Platform ID

BAB648977750

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-NeuN antibody [EPR12763] - Neuronal Marker
Cat. No.AB177487
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Sheep, Goat, Cat, Dog, Human, Zebrafish, Common marmoset
ApplicationFlow Cyt (Intra), mIHC, IHC-Fr, ICC/IF, WB, IHC-P, IHC (PFA fixed)
ClonalityMonoclonal
Clone NumberEPR12763
Concentration0.803 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingConditional Ambient
FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). See full target information NeuN

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