Anti-NeuN antibody - Neuronal Marker,Abcam,AB104225

Anti-NeuN antibody - Neuronal Marker (ab104225) is a rabbit polyclonal antibody and is validated for use in IHC-FoFr, IHC-FrFl, IHC-P, WB in human samples. Anti-NeuN antibody - Neuronal Marker (ab104225) has been cited over 252 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-NeuN antibody - Neuronal Marker (ab104225) has high sensitivity and specificity. Anti-NeuN antibody - Neuronal Marker (ab104225) has 11 independent reviews from customers. Anti-NeuN antibody - Neuronal Marker (ab104225) specifically detects NeuN (UniProt ID: A6NFN3; Molecular weight: 34kDa) and is sold in 50 µL selling sizes. NeuN (RBFOX3), a protein predominantly found in neuronal nuclei and cytoplasm, serves as a key marker for identifying neurons in research. It plays a significant role in the regulation of alternative splicing of pre-mRNA, crucial for neural development and function. Abnormalities in RBFOX3 expression have been implicated in several neurodevelopmental disorders, such as autism spectrum disorder, cognitive impairments, and epilepsy, underscoring its critical role in brain health.

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-FoFr, IHC-FrFl, IHC-P, WB

Platform ID

BAB461533973

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-NeuN antibody - Neuronal Marker
Cat. No.AB104225
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-FoFr, IHC-FrFl, IHC-P, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.03% Sodium azide Constituents: PBS, 49.98% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD). See full target information NeuN

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