Anti-Neurofilament heavy polypeptide antibody,Abcam,AB8135

What is this antibody validated in? Anti-Neurofilament heavy polypeptide antibody (ab8135) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-Fr) in Mouse, Rat samples. Trusted by the scientific community Anti-Neurofilament heavy polypeptide (ab8135) was first used in a scientific publication in 2001 and has been cited over 160 times in peer-reviewed journals. Reviewed by scientists Anti-Neurofilament heavy polypeptide (ab8135) has over 25 independent reviews from customers.

Host

Rabbit

Reactivity

Mouse, Rat

Application

WB, IHC-FrFl

Platform ID

BAB586896299

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Neurofilament heavy polypeptide antibody
Cat. No.AB8135
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationWB, IHC-FrFl
ClonalityPolyclonal
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.03% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Neurofilaments usually contain three intermediate filament proteins : NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (PubMed : 22723690). See full target information Nefh

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