Anti-Neurofilament heavy polypeptide antibody [NF421],Abcam,AB187374

Host

Mouse

Reactivity

Rat, Human

Application

ICC, WB, IHC-P

Platform ID

BAB711958769

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Neurofilament heavy polypeptide antibody [NF421]
Cat. No.AB187374
HostMouse
IsotypeIgG1
ReactivityRat, Human
ApplicationICC, WB, IHC-P
ClonalityMonoclonal
Clone NumberNF421
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human NEFH.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Neurofilaments usually contain three intermediate filament proteins : NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). See full target information NEFH

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