Anti-Neurofilament heavy polypeptide (phospho S) antibody [9B12],Abcam,AB315203

Host

Mouse

Reactivity

Rat, Mouse, Cow

Application

IHC-P, WB

Platform ID

BAB899502498

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Neurofilament heavy polypeptide (phospho S) antibody [9B12]
Cat. No.AB315203
HostMouse
IsotypeIgG2b
ReactivityRat, Mouse, Cow
ApplicationIHC-P, WB
ClonalityMonoclonal
Clone Number9B12
Concentration1 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human NEFH phospho S503 + S526 + S532 + S540 + S546 + S552 + S560 + S566 + S574 + S580 + S586 + S594 + S600 + S606 + S614 + S620 + S628 + S634 + S640 + S648 + S654 + S660 + S668 + S674 + S682 + S688 + S696 + S702 + S710 + S724 + S730 + S744 + S752 + S758 + S769 + S793 + S801 + S828.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 8 Preservative: 0.03% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Neurofilaments usually contain three intermediate filament proteins : NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity). See full target information NEFH phospho S503 + S526 + S532 + S540 + S546 + S552 + S560 + S566 + S574 + S580 + S586 + S594 + S600 + S606 + S614 + S620 + S628 + S634 + S640 + S648 + S654 + S660 + S668 + S674 + S682 + S688 + S696 + S702 + S710 + S724 + S730 + S744 + S752 + S758 + S769 + S793 + S801 + S828

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