Anti-Neutrophil defensin 4 antibody - N-terminal,Abcam,AB192765

Target data Host-defense peptide that has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi (PubMed : 15317502, PubMed : 15616305, PubMed : 2500436, PubMed : 2501794, PubMed : 30658057). Exhibits antimicrobial activity against Gram-negative E.coli and E.aerogenes and Gram-positive S.faecalis, S.aureus and B.cereus and the yeast C.albicans (in vitro) (PubMed : 15317502, PubMed : 15616305, PubMed : 17088326, PubMed : 2500436, PubMed : 2501794, PubMed : 30658057). Interacts with pathogenic surface proteins and toxins, such as HIV-1 surface protein gp120 and B.anthracis anthrax lethal factor lef (PubMed : 15620707, PubMed : 30658057). Protects blood cells against infection with HIV-1 (in vitro) (PubMed : 15620707). Inhibits enzymatic activity of B.anthracis lef/anthrax lethal factor (in vitro) (PubMed : 30658057). Inhibits corticotropin (ACTH)-stimulated corticosterone production (in vitro) (PubMed : 2843187). See full target information DEFA4