Anti-Nkx3.1 antibody,Abcam,AB279582

Target data Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate (PubMed : 10215624). Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells (PubMed : 12036903). Plays a role in the formation of minor salivary glands (particularly palatine and lingual glands) (PubMed : 10906459). See full target information Nkx3-1