Anti-Noxa antibody,Abcam,AB23563
Host
Rabbit
Reactivity
Mouse
Application
WB
Platform ID
BAB029462616
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-Noxa antibody
Cat. No.AB23563
HostRabbit
IsotypeIgG
ReactivityMouse
ApplicationWB
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Mouse Pmaip1 aa 50-100. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 7.4 Constituents: Whole serum
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity). Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. See full target information Pmaip1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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