Anti-Nucleolin antibody,Abcam,AB50279

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

Flow Cyt, WB, IP, ICC/IF

Platform ID

BAB031361704

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Nucleolin antibody
Cat. No.AB50279
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationFlow Cyt, WB, IP, ICC/IF
ClonalityPolyclonal
Concentration1.2 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human NCL aa 1-50 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. See full target information NCL

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