Anti-Nucleolin antibody [SPM614] - BSA and Azide free,Abcam,AB212671
ab212671 can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections.
Host
Mouse
Reactivity
Human
Application
ICC, IHC-P
Platform ID
BAB218905433
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
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Product Specifications
Scientific Background
Specifications
NameAnti-Nucleolin antibody [SPM614] - BSA and Azide free
Cat. No.AB212671
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationICC, IHC-P
ClonalityMonoclonal
Clone NumberSPM614
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human NCL.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. See full target information NCL
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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