Anti-Nucleoporin p62/NUP62 antibody [2A],Abcam,AB188413

Host

Rat

Reactivity

Human, African green monkey

Application

IP, ICC/IF, WB

Platform ID

BAB969080349

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Nucleoporin p62/NUP62 antibody [2A]
Cat. No.AB188413
HostRat
IsotypeIgG1
ReactivityHuman, African green monkey
ApplicationIP, ICC/IF, WB
ClonalityMonoclonal
Clone Number2A
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human NUP62 aa 1-300. The exact immunogen used to generate this antibody is proprietary information.
PurityProprietary technique
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 6 - 8.5 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Essential component of the nuclear pore complex (PubMed : 1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed : 1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed : 1915414, PubMed : 24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed : 24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed : 24107630). See full target information NUP62

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