Anti-Nucleoporin p62/NUP62 (phospho T269 + S272) antibody,Abcam,AB183480

Host

Rabbit

Reactivity

Human

Application

WB

Platform ID

BAB844117831

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Nucleoporin p62/NUP62 (phospho T269 + S272) antibody
Cat. No.AB183480
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human Nuclear pore glycoprotein p62 phospho S272 + T269. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Constituents: 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.24% HEPES, 0.01% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Essential component of the nuclear pore complex (PubMed : 1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed : 1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed : 1915414, PubMed : 24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed : 24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed : 24107630). See full target information Nuclear pore glycoprotein p62 phospho S272 + T269

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