Anti-Nucleoside Diphosphate Kinase 7 antibody,Abcam,AB220753

Host

Rabbit

Reactivity

Human

Application

ICC/IF

Platform ID

BAB406649066

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Nucleoside Diphosphate Kinase 7 antibody
Cat. No.AB220753
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF
ClonalityPolyclonal
Concentration0.6 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human Nucleoside diphosphate kinase 7 aa 150-300. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Possesses an intrinsic kinase activity (PubMed : 24807905). Displays 3'-5' exonuclease activity with a preference for single-stranded DNA (PubMed : 16313181). Does not seem to have nucleoside diphosphate kinase activity (PubMed : 16313181, PubMed : 24807905). Functional component of the gamma-tubulin ring complex, implicated in the regulation of the microtubule-nucleating activity of the gamma-tubulin ring complex in centrosomes, in a kinase activity-dependent manner (PubMed : 24807905). Part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed : 36191189). See full target information Nucleoside diphosphate kinase 7

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