Anti-Nup153 antibody [QE5],Abcam,AB24700

What is this antibody validated in? Anti-Nup153 antibody [QE5] (ab24700) is a mouse monoclonal antibody and is validated for use in Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. Trusted by the scientific community Anti-Nup153 [QE5] (ab24700) was first used in a scientific publication in 2005 and has been cited over 60 times in peer-reviewed journals. Reviewed by scientists Anti-Nup153 [QE5] (ab24700) has over 5 independent reviews from customers. Other related products We have a range of other formats of antibody clone [QE5] also available for your convenience: ab24700, Alexa Fluor® 488 - ab204250 , Alexa Fluor® 647 - ab204457 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Human

Application

ICC/IF

Platform ID

BAB532111344

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Nup153 antibody [QE5]
Cat. No.AB24700
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationICC/IF
ClonalityMonoclonal
Clone NumberQE5
Concentration2 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).. (Microbial infection) Interacts with HIV-1 caspid protein P24 and thereby promotes the integration of the virus in the nucleus of non-dividing cells (in vitro).. (Microbial infection) Binds HIV-2 protein vpx and thereby promotes the nuclear translocation of the lentiviral genome (in vitro). See full target information NUP153

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.