Anti-Occludin antibody [EPR20992],Abcam,AB216327
Anti-Occludin antibody [EPR20992] (ab216327) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P, IP and WB. Anti-Occludin antibody [EPR20992] (ab216327) was first used in a scientific publication in 2018 and has been cited over 237 times in peer reviewed journals. It's performance in Western blot in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Occludin antibody [EPR20992] (ab216327) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Occludin antibody [EPR20992] (ab216327) has been confirmed by Western Blot testing in Occludin knockout HAP1 cells. Anti-Occludin antibody [EPR20992] (ab216327) has 8 independent reviews from customers. Anti-Occludin antibody [EPR20992] (ab216327) specifically detects Occludin (UniProt ID: Q16625; Molecular weight: 60kDa) and is sold in a convenient trial size to enable initial testing (10 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR20992 - ab224526 . Occludin is a tight junction protein that plays a crucial role in maintaining the integrity of epithelial and endothelial barriers. In oncology, its downregulation is associated with increased tumorigenic and metastatic potential in cancers such as lung carcinoma, making it a potential prognostic biomarker and therapeutic target. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Dog, Human
Application
IP, WB, ICC/IF, IHC-Fr, Flow Cyt (Intra), IHC-P
Platform ID
BAB595392219

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Occludin antibody [EPR20992]
Cat. No.AB216327
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Dog, Human
ApplicationIP, WB, ICC/IF, IHC-Fr, Flow Cyt (Intra), IHC-P
ClonalityMonoclonal
Clone NumberEPR20992
Concentration0.682 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.. (Microbial infection) Acts as a coreceptor for hepatitis C virus (HCV) in hepatocytes. See full target information OCLN
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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