Anti-Olig2 antibody [EPR2673] - Oligodendrocyte Marker,Abcam,AB109186

Anti-Olig2 antibody [EPR2673] (ab109186) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P, Mass Cytometry and WB. Anti-Olig2 antibody [EPR2673] (ab109186) was first used in a scientific publication in 2012 and has been cited over 161 times in peer reviewed journals. It's performance in IHC in mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Olig2 antibody [EPR2673] (ab109186) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Olig2 antibody [EPR2673] (ab109186) has 21 independent reviews from customers. Anti-Olig2 antibody [EPR2673] (ab109186) specifically detects Olig2 (UniProt ID: Q13516; Molecular weight: 33kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR2673 - ab220796 . Antibody clone EPR2673 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, Alexa Fluor ® 594, Alexa Fluor ® 555, Alexa Fluor ® 568 ( ab225099 , ab225100 , ab300729 , ab300730 , ab302808 ). OLIG2 is a transcription factor crucial in neuro research for its role in the development and differentiation of neural cells. It is particularly important for the formation of oligodendrocytes and motor neurons. Altered OLIG2 expression is linked to various neurological conditions, including gliomas and neurodevelopmental disorders. Researchers use OLIG2 to study neural cell fate and specification, making it essential for understanding the cellular mechanisms underlying brain development and disease. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Shipping conditions update: ambient shipping This product will be delivered at ambient temperature instead of chilled – this is by design. Extensive stability testing confirmed that our products are suitable for shipment under ambient conditions and maintain expected quality. Why the change? It’s part of our commitment to more sustainable packaging solutions, with ambient deliveries using eco-friendly materials such as recyclable cardboard instead of polystyrene. What you need to know Ambient shipments come clearly marked on the delivery note. No ice will be included in ambient shipments, but mixed orders (ambient and cold-chain items) will still arrive with ice packs to protect temperature-sensitive products. Warranty coverage remains fully valid, aligned with our validated shipping method. Please store the product as per the datasheet instructions upon receipt. Find out more - https://www.abcam.com/en-us/support/shipping-storage-support/ambient-shipping

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IMC™, WB, ICC/IF, IHC-P, IHC-Fr

Platform ID

BAB658473190

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Olig2 antibody [EPR2673] - Oligodendrocyte Marker
Cat. No.AB109186
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIMC™, WB, ICC/IF, IHC-P, IHC-Fr
ClonalityMonoclonal
Clone NumberEPR2673
Concentration0.135 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingConditional Ambient
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Functions together with ZNF488 to promote oligodendrocyte differentiation. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. See full target information OLIG2

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