Anti-Orexin A antibody,Abcam,AB6214

What is this antibody validated in? Anti-Orexin A antibody (ab6214) is a rabbit polyclonal antibody and is validated for use in Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), ELISA in Cow, Mouse, Rat samples. Trusted by the scientific community Anti-Orexin A (ab6214) was first used in a scientific publication in 2000 and has been cited over 10 times in peer-reviewed journals.

Host

Rabbit

Reactivity

Rat, Mouse, Cow

Application

IHC-P, IHC-FoFr, ELISA, IHC-Fr

Platform ID

BAB096441715

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Orexin A antibody
Cat. No.AB6214
HostRabbit
IsotypeIgG
ReactivityRat, Mouse, Cow
ApplicationIHC-P, IHC-FoFr, ELISA, IHC-Fr
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Cow HCRT aa 1 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 7.4
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested.. Orexin-A. Binds to orexin receptors HCRTR1/OX1R and HCRTR2/OX2R with a high affinity (By similarity). Stimulates food intake (By similarity). Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner (By similarity).. Orexin-B. Binds to orexin receptor HCRTR2/OX2R only (By similarity). Stimulates food intake (By similarity). Modulates pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner (By similarity). See full target information HCRT

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