Anti-Osteopontin antibody,Abcam,AB8448

Product Specifications Anti-Osteopontin antibody (ab8448) is a rabbit polyclonal antibody and is validated for use in IHC-P in human samples. Anti-Osteopontin antibody (ab8448) specifically detects Osteopontin (UniProt ID: P10451; Molecular weight: 34kDa) and is sold in 200 µL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-Osteopontin antibody (ab8448) has high sensitivity and specificity. Anti-Osteopontin antibody (ab8448) has been cited over 445 times in peer reviewed journals and is trusted by the scientific community. Anti-Osteopontin antibody (ab8448) has 14 independent reviews from customers.

Host

Rabbit

Reactivity

Human

Application

IHC-P

Platform ID

BAB097041427

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Osteopontin antibody
Cat. No.AB8448
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human SPP1 aa 150-200 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.01% Sodium azide Constituents: 98.6% Whole serum, 0.88% Sodium chloride, 0.424% Potassium phosphate solution
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. See full target information SPP1

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