Anti-Osteoprotegerin antibody,Abcam,AB9986
This product is no longer batch tested in IHC, for an IHC validated antibody please see ab124820
Host
Rabbit
Reactivity
Human
Application
WB
Platform ID
BAB034660120
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Osteoprotegerin antibody
Cat. No.AB9986
HostRabbit
IsotypeUnknown
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
ImmunogenRecombinant Fragment Protein within Human TNFRSF11B. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLyophilized
ShippingBlue Ice
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Acts as a decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. See full target information TNFRSF11B
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.