Anti-Osteoprotegerin antibody,Abcam,AB183910
Host
Rabbit
Reactivity
Mouse, Human, Rat
Application
IHC-P, WB
Platform ID
BAB097141379
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Osteoprotegerin antibody
Cat. No.AB183910
HostRabbit
IsotypeIgG
ReactivityMouse, Human, Rat
ApplicationIHC-P, WB
ClonalityPolyclonal
Concentration1.48 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human TNFRSF11B aa 1-100. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Acts as a decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. See full target information TNFRSF11B
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.