Anti-Otoferlin antibody [13A9],Abcam,AB53233

What is this antibody validated in? Anti-Otoferlin antibody [13A9] (ab53233) is a mouse monoclonal antibody and is validated for use in Flow Cytometry (Flow Cyt), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. Trusted by the scientific community Anti-Otoferlin [13A9] (ab53233) was first used in a scientific publication in 2007 and has been cited over 30 times in peer-reviewed journals.

Host

Mouse

Reactivity

Mouse, Human

Application

Flow Cyt, ICC/IF

Platform ID

BAB409747578

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Otoferlin antibody [13A9]
Cat. No.AB53233
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationFlow Cyt, ICC/IF
ClonalityMonoclonal
Clone Number13A9
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Protein within Human OTOF aa 1-400. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: 2% Sucrose, 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion and in the control of neurotransmitter release at these output synapses. Interacts in a calcium-dependent manner to the presynaptic SNARE proteins at ribbon synapses of cochlear inner hair cells (IHCs) to trigger exocytosis of neurotransmitter. Also essential to synaptic exocytosis in immature outer hair cells (OHCs). May also play a role within the recycling of endosomes (By similarity). See full target information OTOF

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