Anti-P-Selectin (CD62P) antibody [Psel.KO.2.5],Abcam,AB118522

Host

Mouse

Reactivity

Human

Application

IHC-P, Flow Cyt

Platform ID

BAB816553597

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-P-Selectin (CD62P) antibody [Psel.KO.2.5]
Cat. No.AB118522
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationIHC-P, Flow Cyt
ClonalityMonoclonal
Clone NumberPsel.KO.2.5
Concentration1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing SELP protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG. Mediates cell-cell interactions and cell adhesion via the interaction with integrin alpha-IIb/beta3 (ITGA2B : ITGB3) and integrin alpha-V/beta-3 (ITGAV : ITGB3) (PubMed : 37184585). See full target information SELP

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